ea0020oc4.6 | Acromegaly/IGF1/Type 2 Diabetes | ECE2009
Isidori Andrea
, Giannetta Elisa
, Carbone Iacopo
, Vizza Dario
, Orano Susanna
, Vingolo Enzo
, Bonifacio Vincenzo
, Lenzi Andrea
In type 2 diabetes (T2DM), cardiomiopathy is characterized by an impairment of diastolic performance resulting in ventricular hypertrophy and dilatation. Heart remodelling leads to an increase in its angle of torsion, measurable by innovative cine-magnetic resonance imaging (MRI). To evaluate the impact of phosphodiesterase 5 inhibitors (PDE5i) on cardiovascular performance in T2DM, we designed a randomized, placebo-controlled, double blind (subject/outcome assessor) study on ...